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Choline – Overview, Dosage, Side Effects & Research

What is Choline?


Choline is a nootropic, or cognitive enhancer supplement, which is used to improve memory. Choline has also been to known to help with:


·       Mental clarity

·       Attention / Concentration

·       Focus

·       Mood

·       Memory


Choline is part of the B Vitamin family and has shown relatively little known side effects. Choline is used to treat:


·       Alzheimer’s Disease


Choline is naturally found in foods such as eggs, meat, liver, fish and beans. Choline is often recommended for users of nootropics such as piracetam as the body’s need for choline is increased during supplementation.


What is the best Choline dosage?


It is recommended the average man take 550 mg Choline minimum, whether by supplement or through food ingestion. The average women needs 425 mg Choline minimum. It is recommended – racetam users experiment with optimal Choline doses.


The maximum recommended daily intake for Choline in adults is 3.5g.


What are the side effects of Choline?


If people take high doses of Choline they may experience some side effects. These effects include:

·       Nausea

·       Vomiting

·       Diarrhea

·       Increased sweatiness


There is some concern Choline supplementation could promote cardiovascular disease. However more research is needed for proper determination.


How does Choline work?


Choline works by affecting the neurotransmitter Acetylcholine. Choline increases the amount of acetylcholine produced. Acetylcholine holds the honor of first ever identified neurotransmitter. It affects both the central and peripheral nervous system. Acetylcholine plays a cardinal role in the way our brain regulates information processing and memory related functions. An inadequacy in acetylcholine / choline could be detrimental for memory recall, memory loss, and the building of new memories.


History / Studies of Choline


There have been many studies testing the effects on Choline in human patients. One such study says:

“Ninety-two patients affected by chronic cerebrovasculopathy were treated with cytidine diphosphate choline ( CDP-choline ) 1000 mg/day i.m. or with placebo, in a double-blind study. Two cycles of therapy of 4 weeks each were performed, with an interval of 1 week. There were 46 patients in each group with chronic cerebrovascular diseases, and the two groups were comparable as far as mental deterioration was concerned. The comparison between the two groups revealed significant improvements in the CDP-choline group compared with the placebo group in some of the attention capabilities. No side-effects were detected in the CDP-choline group.”